KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
14.55
Human Site:
T94
Identified Species:
24.62
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
T94
S
K
N
N
E
G
L
T
K
L
P
F
T
I
P
Chimpanzee
Pan troglodytes
XP_511585
968
108684
T91
N
G
D
G
L
V
V
T
V
D
S
E
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
T187
S
K
N
N
E
G
L
T
K
L
P
F
T
I
P
Dog
Lupus familis
XP_853409
975
109686
T94
G
K
N
N
E
G
L
T
K
L
P
F
T
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
T96
G
K
N
N
E
G
L
T
K
L
P
F
T
I
P
Rat
Rattus norvegicus
XP_573211
965
109012
V94
P
F
T
I
P
E
L
V
Q
A
S
P
C
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
I92
Y
M
G
K
K
Q
D
I
W
Y
V
V
D
L
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
M99
G
R
N
K
E
G
L
M
K
L
P
F
T
I
Q
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
P92
K
E
G
L
M
K
L
P
F
T
I
Q
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
V93
V
A
E
H
Q
E
N
V
Q
V
P
H
F
L
P
Honey Bee
Apis mellifera
XP_392044
968
110555
G92
V
K
V
P
V
E
L
G
R
T
S
M
P
M
F
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
L106
K
N
S
S
L
K
K
L
P
F
N
I
P
Q
L
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
K116
G
P
G
G
D
G
L
K
K
L
P
L
T
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
N94
T
A
D
N
R
R
A
N
K
K
G
R
R
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
0
N.A.
66.6
6.6
N.A.
13.3
13.3
0
53.3
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
13.3
N.A.
13.3
N.A.
73.3
20
N.A.
46.6
26.6
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
8
0
0
8
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
15
0
8
0
8
0
0
8
0
0
8
0
8
% D
% Glu:
0
8
8
0
36
22
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
8
0
36
8
0
8
% F
% Gly:
29
8
22
15
0
43
0
8
0
0
8
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
8
8
0
43
0
% I
% Lys:
15
36
0
15
8
15
8
8
50
8
0
0
0
0
0
% K
% Leu:
0
0
0
8
15
0
65
8
0
43
0
8
0
22
8
% L
% Met:
0
8
0
0
8
0
0
8
0
0
0
8
0
8
8
% M
% Asn:
8
8
36
36
0
0
8
8
0
0
8
0
0
0
0
% N
% Pro:
8
8
0
8
8
0
0
8
8
0
50
8
15
0
43
% P
% Gln:
0
0
0
0
8
8
0
0
15
0
0
8
0
8
8
% Q
% Arg:
0
8
0
0
8
8
0
0
8
0
0
8
8
8
0
% R
% Ser:
15
0
8
8
0
0
0
0
0
0
22
0
8
0
8
% S
% Thr:
8
0
8
0
0
0
0
36
0
15
0
0
43
0
0
% T
% Val:
15
0
8
0
8
8
8
15
8
8
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _